Seneca Post Office

508 E Main St, Seneca, SC 29678

Contact Numbers:

Phone: 864-882-8422
Fax: 864-885-0443
TTY: 877-889-2457
Toll-Free: 1-800-Ask-USPS® (275-8777)

Retail Hours

Bulk Mail Acceptance Hours

Monday-Friday 10:30am - 4:00pm
Saturday-Sunday Closed

Pickup Services Hours

Monday-Friday 10:00am - 5:00pm
Saturday-Sunday Closed

Lobby Hours

Monday-Sunday 12:01am - 11:59pm

PO Box Access Hours

Monday-Sunday 12:01am - 11:59pm

PO Box Delivery Time

Monday-Saturday 10:30am
Sunday Closed

Last Collection Times

Monday-Friday 5:00pm
Saturday 2:00pm
Sunday Closed

Carrier Facility Hours

Monday-Friday 10:00am - 4:30pm
Saturday 10:00am - 12:00pm
Sunday Closed

Global Express Guaranteed® Hours

Monday-Friday 10:00am - 5:00pm
Saturday 10:00am - 12:00pm
Sunday Closed

*This facility does not process US Passports applications or renewals. Check nearby locations below.

  • Bulk Mail Acceptance
  • Bulk Mail Account Balance
  • Bulk Mail New Permit
  • Burial Flags
  • Business Reply Mail Account Balance
  • Business Reply Mail New Permit
  • Duck Stamps
  • General Delivery
  • Global Express Guaranteed®
  • Money Orders (Domestic)
  • Money Orders (Inquiry)
  • Money Orders (International)
  • Pickup Accountable Mail
  • Pickup Hold Mail
  • PO Box Online
  • Priority Mail International®
  • Lot Parking

Visit our Links Page for Change of Address, Hold Mail/Stop Delivery, PO Boxes™ rentals and fees, Rates on Postage Stamps and Freight/Shipping, Holidays, Bulk Mail, Money Orders, and Available Jobs.

*Please call to verify information. Is anything incorrect? Let us know here

Nearby Post Offices:

701a Broadway St
2.3 miles away

304 Richland Rd
3.2 miles away

519 College Ave
4.5 miles away

West Union
190 S Highway 11
4.9 miles away


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We did not get a pick up or delivery on Thursday, 4/06/17 on Waterside Cove off Coneross Creek Rd. No debris down from the storm and nothing blocking any of the mailboxes.


Our postal carrier from USPS is absolutely rediculous and clearly not qualified for the job. I cannot even recall all of the times that our post is put in the wrong mailbox. Recently there were parcel boxes installed in our neighborhood in an attempt to solve prior issues. Well needless to say this has not solved the problem but simply made it more frustrating. We as tenants are delivering packages to various buildings because the postal carrier cannot do their job. I assure you we do not pay for additional postage to ensure our items arrive on time only for the carrier to place it in the wrong boxes all together. Our packages are now locked in one of the four parcel boxes which are locked and we cannot get to. This problem needs to be fixed!


I live at 250 Kelly Mill Rd, Seneca,S C. I left 2 bags of food for the hungry at my mailbox and the driver just came by and drove off without it. I am disappointed to say the least.

* is not a part of, or affiliated with, the official United States Postal Service (USPS).